Browsing Tag estrogen

Why soya is not good for you.

For the last twenty years, tofu has been all the rage. As people became increasingly educated about the dangers of dairy and dairy products, tofu became the viable substitute. However in a bizarre reversal of sorts, we have begun to discover that if a little of something is good, more of it is not necessarily better. “Tofu Shrinks Brain!” Not a science fiction scenario, this sobering soybean revelation is for real. But how did the “poster bean” of the ’90s go wrong? Apparently, in many ways – none of which bode well for the brain.

In a major ongoing study involving 3,734 elderly Japanese-American men, those who ate the most tofu during midlife had up to 2.4 times the risk of later developing Alzheimer’s disease. As part of the three-decade long Honolulu-Asia Aging Study, 27 foods and drinks were correlated with participants’ health. Men who consumed tofu at least twice weekly had more cognitive impairment, compared with those who rarely or never ate the soybean curd.

“The test results were about equivalent to what they would have been if they were five years older,” said lead researcher Dr. Lon R. White from the Hawaii Center for Health Research. For the guys who ate no tofu, however, they tested as though they were five years younger.

What’s more, higher midlife tofu consumption was also associated with low brain weight. Brain atrophy was assessed in 574 men using MRI results and in 290 men using autopsy information. Shrinkage occurs naturally with age, but for the men who had consumed more tofu, White said “their brains seemed to be showing an exaggeration of the usual patterns we see in aging.”

Phytoestrogens – Soy Self Defense

Tofu and other soybean foods contain isoflavones, three-ringed molecules
bearing a structural resemblance to mammalian steroidal hormones. White and his fellow researchers speculate that soy’s estrogen-like compounds (phytoestrogens) might compete with the body’s natural estrogens for estrogen receptors in brain cells.

Plants have evolved many different strategies to protect themselves from predators. Some have thorns or spines, while others smell bad, taste bad, or
poison animals that eat them. Some plants took a different route, using birth
control as a way to counter the critters who were wont to munch.

Plants such as soy are making oral contraceptives to defend themselves, says
Claude Hughes, Ph.D., a neuroendocrinologist at Cedars-Sinai Medical Center.They evolved compounds that mimic natural estrogen. These phytoestrogens caninterfere with the mammalian hormones involved in reproduction and growth – a strategy to reduce the number and size of predators.

Toxicologists Concerned About Soy’s Health Risks

The soy industry says that White’s study only shows an association between tofu consumption and brain aging, but does not prove cause and effect. On the other hand, soy experts at the National Center for Toxicological Research, Daniel Sheehan, Ph.D., and Daniel Doerge, Ph.D., consider this tofu study very important. “It is one of the more robust, well-designed prospective epidemiological studies generally available. . . We rarely have such power in human studies, as well as a potential mechanism.”

In a 1999 letter to the FDA (and on the ABC News program 20/20), the two
toxicologists expressed their opposition to the agency’s health claims for soy, saying the Honolulu study “provides evidence that soy (tofu) phytoestrogens cause vascular dementia. Given that estrogens are important for maintenance of brain function in women; that the male brain contains aromatase, the enzyme that converts testosterone to estradiol; and that isoflavones inhibit this enzymatic activity, there is a mechanistic basis for the human findings.”

Although estrogen’s role in the central nervous system is not well understood, White notes that “a growing body of information suggests that estrogens may be needed for optimal repair and replacement of neural structures eroded with aging.”

One link to the puzzle may involve calcium-binding proteins, which are
associated with protection against neurodegenerative diseases. In recent
animal studies at Brigham Young University’s Neuroscience Center, researchers found that consumption of phytoestrogens via a soy diet for a relatively short interval can significantly elevate phytoestrogens levels in the brain
and decrease brain calcium-binding proteins.

Concerns About Giving Soy to Infants

The most serious problem with soy may be its use in infant formulas. “The
amount of phytoestrogens that are in a day’s worth of soy infant formula equals 5 birth control pills,” says Mary G. Enig, Ph.D., president of the Maryland Nutritionists Association. She and other nutrition experts believe that infant exposure to high amounts of phytoestrogens is associated with early puberty in girls and retarded physical maturation in boys.

A study reported in the British medical journal Lancet found that the “daily
exposure of infants to isoflavones in soy infant-formulas is 6-11 fold higher on a bodyweight basis than the dose that has hormonal effects in adults consuming soy foods.” (A dose, equivalent to two glasses of soy milk per day, that was enough to change menstrual patterns in women. ) In the blood of infants tested, concentrations of isoflavones were 13000-22000 times higher than natural estrogen concentrations in early life.

Soy Interferes with Enzymes

While soybeans are relatively high in protein compared to other legumes, Enig says they are a poor source of protein because other proteins found in soybeans act as potent enzyme inhibitors. These “anti-nutrients” block the action of trypsin and other enzymes needed for protein digestion. Trypsin inhibitors are large, tightly folded proteins that are not completely deactivated during ordinary cooking and can reduce protein digestion. Therefore, soy consumption may lead to chronic deficiencies in amino acid
uptake.

Soy’s ability to interfere with enzymes and amino acids may have direct consequence for the brain. As White and his colleagues suggest, “isoflavones in tofu and other soyfoods might exert their influence through interference with tyrosine kinase-dependent mechanisms required for optimal hippocampal function, structure and plasticity.”

High amounts of protein tyrosine kinases are found in the hippocampus, a
brain region involved with learning and memory. One of soy’s primary
isoflavones, genistein, has been shown to inhibit tyrosine kinase in the
hippocampus, where it blocked “long-term potentiation,” a mechanism of memory formation.

Be well

Dr Sundardas


February 24, 2009 By : admin Category : allergies Tags:dairy products, estrogen, isoflavones, phytoestrogens, tofu, Why soya is not good for us
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Beating Fatigue

You get your nine hours of beauty sleep regularly every night. So why do you feel so tired? You eat all the right foods or so you think. You regularly exercise thirty minutes a day. However you just can’t seem to get up and go. Even sex seem to be a chore. If so read on…

If you are fatigued and have trouble falling asleep, or sleeping restfully, suspect that caffeine may be the cause when: You drink any caffeinated beverage within three hours of bedtime You drink the equivalent of five or more cups of coffee per day You become aware that small caffeine increase makes you restless, excited, super-alert or nervous. You may suspect that your fatigue may be caused by caffeine overstimulation, if you drink the equivalent of five or more cups of coffee per day and if you suffer symptoms of physical hyperstimulation or a sense of depletion. If cutting down on your coffee makes you feel better, you have discovered the source of your problem.

Do you remember the times you used to feel depressed and out of sorts? Do you remember what you craved to eat at that point in time? Was it fruits and nuts? Was it salad and fruit juice? Most of you at such times would have gone for sweet things like chocolate, cookies and candies or ice-creams

The initial rush of energy or lift that you get occurs because these food products are quickly metabolised to produce blood sugar.This is precisely what happens when you crave your mid-morning cup of coffee with sugar. Initially you will get a temporary energy lift since it raises your blood sugar level. This is followed soon by a downward plunge of energy leaving you feeling worse than before, calling for a repetition of more coffee and sweets or alcohol.

When we have a simpler way of life we would strike at our enemy or run away for an emergency. The event would end and the body would return to a more normal relaxed state. In everyday situations however we are confronted with a series of stresses that arouse our bodies in the same fashion as a fight/flight emergency.. No wonder you are tired. However many individuals don’t feel their emotions of anger, impatience, frustration or depression and despair. They may be so accustomed to being worried or hostile that they think the condition is normal. Meanwhile their bodies are falling apart as they tax it to the limit. Fatigue is the inevitable outcome.

If you want to have a constant supply of energy, forget the “three square meals ad day” rule. Most meal aren’t square anyway but are likely to be unbalanced or inadequate anyway. Eat like a rabbit or squirrel. Nibble your way through healthy snacks. No, I am not suggesting that you snack on ice-cream, chocolates and sweets or pastries.

Eat health foods that build up your energy level consistently. Substitute protein for sweets and carbohydrates at your many meals. Snack on slices of fruits, nuts, a piece of raw fruit, a celery or a carrot stick.

Make a protein powder drink with your fruit juice for breakfast or lunch and you will have the juice of life to burn for hours. If you plan to attend an important meeting after lunch and you need to be mentally alert than skip the carbohydrates during lunch. Have a salad with some fish or chicken.

You could even try a protein drink with fruit juice. Sometimes though, you happen to be a really nervy type. You want to deliberately calm down and slow down at the meeting. That is when you would want to snack on rice and vegetables.

Skip the protein foods for they will make you overly alert. Another quick energy boosting routine is to eat a little fat. That’s right fat. I can imagine some of you shaking your head and thinking “Now I have really heard it all”.

Researchers have learnt that a little fat is necessary to make your gall bladder work. I have heard of horror stories of people who have had their gall bladder shut down on them because went they went on a diet and did not take any fat at all. They needed surgery after that.

Taking a little fat staves of hunger as well as fatigue for hours, Either add a bit ofcold-pressed vegetable oil to your protein drink before you blend it (you will never notice it there) or add more oil to your salad at mealtimes and drink only the remains from the bowl.

After almost 19 years of seeing clients with a range of fatigue conditions, we have come to the following factors that could underlie as serious case of fatigue. These factors are

Allergies
Chemical Poisons
Heavy Metal Toxicity
Candida
Parasites
Dental issues
Nutritional Deficiencies
Hypoglycemia
Hypothyroid
Structural Issues
Emotional Issues
Estrogen Dominance – Progesterone Deficiency

Be well

Dr Sundardas

February 24, 2009 By : admin Category : importance of wellness Tags:Allergies Chemical Poisons, Candida, Deficiency, Dental issues, Dominance – Progesterone, estrogen, Heavy Metal Toxicity, Hypoglycemia, Hypothyroid, Nutritional Deficiencies, Parasites, Structural Issues Emotional Issues
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